Science Crossword Puzzles: Free Printable and Online

Explore the fundamental principles and latest discoveries across physics, chemistry, biology, and astronomy. This topic covers scientific methods and breakthroughs.

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Nobel Prize Week

Medium · 11×11 · 15 words
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  1. 1. Basic particle manipulated in many Chemistry and Physics prize-winning discoveries
  2. 3. Kenso ___, co-winner of the 2026 Chemistry prize for asymmetric autocatalysis
  3. 5. Biological unit combined with optics in a revolutionary 2026 prize-winning technique
  4. 7. Henri B. ___, 2026 Chemistry laureate recognized for work on non-linear effects
  5. 9. Swedish capital where the scientific and literary prizes are awarded
  6. 12. Light-gated ___ channels were key to the 2026 Medicine prize
  7. 13. Alfred ___, the Swedish chemist who endowed the prestigious awards
  8. 14. Prize category awarded in 2026 for the discovery of optogenetics

Down

  1. 1. Aquatic organisms from which light-sensitive proteins were isolated for optogenetics
  2. 2. Royal figure who presents the Nobel Prizes in Sweden
  3. 4. Explosive invention that funded the prestigious Swedish prizes
  4. 6. Elusive ghost particle detected by the IceCube observatory
  5. 8. South Pole neutrino observatory honored by the 2026 Physics prize
  6. 10. Norwegian capital where the Peace Prize is handed out
  7. 11. Historic 1895 document that established the five original Nobel Prizes

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Deep space astronomy

Medium · 15×15 · 22 words
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  1. 1. Category of compact galaxy that frequently orbits larger spiral systems
  2. 4. Gravitational distortion of spacetime geometry caused by massive bodies
  3. 6. Galactic morphology characterized by pinwheel-like stellar arms
  4. 8. Interstellar cloud of dust and gas where stars are born or die
  5. 10. Sudden stellar outburst that temporarily outshines its neighbors
  6. 13. Describing the vast physical space between individual star systems
  7. 15. Circular band of ionized gas seen in the constellation Lyra, cataloged as M57
  8. 16. Vast, empty expanse between cosmic web filaments
  9. 18. Flattened, rotating plane hosting the spiral arms of galaxies
  10. 19. NASA space observatory specialized in high-energy X-ray astronomy
  11. 20. Dense central hub of a globular cluster or galaxy

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  1. 2. Nearby southern galaxy cluster known for its bright central elliptical galaxy NGC 1399
  2. 3. Standard mass benchmark based on our home star used to weigh black holes
  3. 4. Infrared space telescope operating near the Earth-Sun L2 point
  4. 5. Cosmic phenomenon where massive clusters bend background light into arcs or rings
  5. 6. Theoretical point of infinite density at the center of a black hole
  6. 7. Gravitationally bound system containing hundreds or thousands of galaxies
  7. 9. Process where matter spirals onto a compact object, releasing gravitational energy
  8. 11. Nearest major spiral galaxy headed for an eventual merger with our own
  9. 12. Logarithmic measure of a celestial object's brightness
  10. 14. Astronomical unit of length equal to roughly 3.26 light-years
  11. 17. Microscopic solid grains that scatter ultraviolet light and obscure distant nebulae

Spooky Science

Medium · 11×11 · 15 words
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  1. 1. Inevitable biological breakdown transforming flesh into earth
  2. 5. Biochemical cocktail delivered via fangs or a wicked stinger
  3. 7. Deceased body donated to the chilly confines of medical school
  4. 8. Flying mammal guided by ghostly acoustic echoes in the dark
  5. 11. Fortress of bubbling flasks and late-night monster creation
  6. 12. Thick, glowing slime seeping from a cracked containment barrel
  7. 13. Mysterious sensation felt in a limb that is no longer there
  8. 14. Entity straddling the eerie border between nonliving chemical and living invader

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  1. 1. Methodically carve open a biological specimen to expose inner workings
  2. 2. Cylindrical glassware often filled with smoking concoctions
  3. 3. Skeletal remain that endures long after tissues decompose
  4. 4. Real-world fungus notorious for turning insects into mind-controlled zombies
  5. 6. Delicate yet deadly protein trap spun in shadowy corners
  6. 9. Odorless radioactive gas that sneaks up from subterranean rock
  7. 10. Invisible beam capable of seeing straight through human flesh

Genetics & DNA

Medium · 11×11 · 12 words
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  1. 4. Microscopic chamber where genetic material is housed
  2. 6. Genetically determined characteristic such as eye color
  3. 7. Trait that appears only when two copies of an allele are present
  4. 9. Purine base represented by the letter G in the genetic code
  5. 11. Organism that is an exact genetic replica of another

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  1. 1. DNA vehicle used to transfer foreign material into a host
  2. 2. Permanent alteration in the nucleotide sequence of a strand
  3. 3. Complete set of genetic instructions within an organism
  4. 5. Base that pairs with guanine across three hydrogen bonds
  5. 8. Set of molecular rules mapping triplets to amino acids
  6. 9. Basic physical unit of biological inheritance
  7. 10. Expressed segment retained in mature messenger RNA

World Space Week

Medium · 11×11 · 16 words
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  1. 1. Extraterrestrial life form
  2. 3. The central star of our solar system
  3. 6. The universe seen as a well-ordered whole
  4. 8. A glowing sphere of plasma, like Sirius
  5. 12. When one celestial body obscures another
  6. 14. An icy body that releases gas or dust
  7. 15. The famous dwarf planet in the Kuiper belt
  8. 16. A massive system of stars, like the Milky Way

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  1. 2. The Roman goddess of the moon, or the moon itself
  2. 4. US agency behind the Artemis missions
  3. 5. Focused beam of light used in some satellite communications
  4. 7. Reaching this path is becoming cheaper thanks to reusable rockets
  5. 9. The vehicle at the center of the 2026 World Space Week "Revolution" theme
  6. 10. A giant cloud of dust and gas in the universe
  7. 11. The amount of gravity experienced in free fall
  8. 13. Earth's natural satellite

auskultatsiya

Easy · 5×5 · 5 words
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  1. 2. The substance that moves through the respiratory tract to create audible sounds.
  2. 4. The area of the body where a stethoscope is typically placed.

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  1. 1. A common nickname for the professional who performs an auscultation.
  2. 3. The speed at which a pulse or heartbeat occurs.
  3. 5. The primary organ used for listening to body sounds.

narcolepsy

Medium · 11×11 · 14 words
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  1. 2. Sudden temporary loss of voluntary muscle tone triggered by strong emotions
  2. 4. Stage of sleep marked by rapid eye movement and vivid dreams
  3. 6. Briefly droop the head while drifting off during conversation
  4. 8. Disease mechanism where the body's defenses mistakenly attack its own tissues
  5. 12. Fully conscious, attentive, and ready to respond to stimuli
  6. 13. Inability to maintain continuous slumber through the nocturnal hours

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  1. 1. Brief period of rest often taken strategically to manage daytime fatigue
  2. 2. Relating to the twenty-four-hour biological clock that guides daily sleep cycles
  3. 3. Fall into a light or fitful slumber without meaning to
  4. 5. Prolonged state of profound unconsciousness, distinct from sudden sleep attacks
  5. 7. Period of darkness often plagued by fragmented slumber in affected individuals
  6. 9. Feeling a persistent drain of bodily vitality
  7. 10. Specialized brain cell that transmits signals, some of which produce hypocretin
  8. 11. Disorder causing paused breathing during rest, often evaluated alongside narcolepsy

science

Easy · 5×5 · 4 words
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  1. 3. The form of energy that allows us to see
  2. 4. A massive luminous sphere of plasma in space

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  1. 1. The smallest structural unit of a living organism
  2. 2. A clear liquid essential for all known life

element, periodic table, chemical symbol, compound, chemical formula, physical change, chemical change

Medium · 11×11 · 14 words
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  1. 4. Inert noble gas glowing reddish-orange in high-voltage signs
  2. 6. Pure substance composed entirely of atoms with identical proton counts
  3. 7. Malleable post-transition metal designated by Sn
  4. 9. Substance that accelerates a reaction without being consumed
  5. 12. Binary compound containing oxygen bound to another element
  6. 13. Attractive forces that hold atoms together within molecules
  7. 14. Dense, toxic heavy metal bearing the symbol Pb

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  1. 1. Shift from a rigid solid into a fluid state by absorbing heat
  2. 2. Rapid exothermic chemical reaction between fuel and an oxidant
  3. 3. Ubiquitous compound composed of two hydrogens and one oxygen
  4. 5. Chemical change characterized by the loss of electrons
  5. 8. Outermost electrons responsible for dictating chemical reactivity
  6. 10. Undergo a rapid phase transition from liquid into vapor
  7. 11. Flaky reddish product of iron reacting with oxygen and water

element, periodic table, chemical symbol, compound, chemical formula, physical change chemical change

Medium · 11×11 · 14 words
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  1. 1. Flaky reddish product formed by iron oxidation
  2. 3. Lustrous, conductive element located on the left and center of the table
  3. 8. Undergo a physical change from solid to liquid
  4. 9. Substance formed when two or more elements chemically unite
  5. 11. Ionic compounds produced alongside water during acid-base neutralization
  6. 13. Binary compound containing oxygen combined with another element
  7. 14. Inert noble gas famous for brilliant reddish-orange signage

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  1. 2. Direct physical phase change from solid to gas without melting
  2. 4. Pure chemical substance that cannot be broken down by ordinary reactions
  3. 5. Versatile tetravalent backbone of all organic molecules
  4. 6. Starting material consumed during a chemical transformation
  5. 7. Basic building block of all chemical elements
  6. 10. Dense element denoted by the symbol Pb
  7. 12. Magnetic metal whose symbol derives from ferrum
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