Biology Crossword Puzzles: Free Printable and Online

Unravel the complexities of life itself, from microscopic cells to sprawling ecosystems. Explore genetics, evolution, and the wonders of the natural world.

Print any biology crossword below, download it as a PDF, or play it online. Free, and no signup is needed to play.

10 puzzles, click Print on any puzzle below

Biology

Easy · 7×7 · 8 words
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Across

  1. 1. The small part of a plant that can grow into a new one
  2. 4. An organ used for breathing air
  3. 6. The organ used for seeing
  4. 7. A fiber that sends signals to the brain

Down

  1. 1. The outer layer of the body
  2. 2. The molecule that carries genetic information
  3. 3. The basic unit of all living things
  4. 5. A segment of DNA that determines a trait

Simple biology cells knowledge

Easy · 7×7 · 7 words
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Across

  1. 1. Any tiny part of a cell with a specific job
  2. 5. The scientific name for the cell control center
  3. 7. A small segment of DNA that determines a trait

Down

  1. 2. The simple sugar that cells use for fuel
  2. 3. The genetic material that carries instructions for life
  3. 4. A long cell that sends signals to the brain
  4. 6. Cells that form a protective layer over the body

Biology

Easy · 7×7 · 9 words
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Across

  1. 1. The small part of a plant that can grow into a new one
  2. 4. An organ used for breathing air
  3. 7. The organ used for seeing
  4. 8. The main trunk of a plant that supports leaves

Down

  1. 1. The outer layer covering a human body
  2. 2. An oval object from which a baby animal hatches
  3. 3. The basic building block of all living things
  4. 5. A tiny living thing that can cause disease
  5. 6. The part of a plant where photosynthesis usually happens

Life Cycles

Medium · 15×15 · 14 words
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Across

  1. 1. Earliest stage of a developing plant or animal, before birth or hatching
  2. 5. Young animal that has not yet reached adulthood
  3. 10. Immature, wingless feeding stage between egg and pupa in many insects
  4. 12. Process of a seed beginning to sprout and grow into a plant
  5. 13. Young insect that looks like a small adult and lacks a pupal stage
  6. 14. Total length of time an organism is expected to live

Down

  1. 2. Young produced by an animal or plant
  2. 3. Final, sexually mature stage of an organism's life cycle
  3. 4. Non-feeding stage during which an insect's body is completely rebuilt into its adult form
  4. 6. Describes a life cycle with only three main stages
  5. 7. Transfer of pollen that allows a flowering plant to produce seeds
  6. 8. Describes metamorphosis with four distinct stages, including a pupa
  7. 9. All the offspring born and living around the same time
  8. 11. To produce offspring of the same species

Life Cycles

Easy · 11×11 · 12 words
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Across

  1. 2. Resting stage between larva and adult in many insects
  2. 5. To break out of an egg
  3. 6. Adult amphibian that hops and can live on land or water
  4. 8. Hard protective case a caterpillar forms before becoming a butterfly
  5. 10. Fully grown stage of an animal's life cycle
  6. 12. Colorful part of a plant that helps it make seeds

Down

  1. 1. Flying insect with colorful wings that starts life as a caterpillar
  2. 3. Part of a plant that grows from a flower and holds seeds
  3. 4. Round object where many animals begin life
  4. 7. Young frog that lives in water and breathes with gills
  5. 9. Worm-like young stage of an insect after it hatches
  6. 11. Small part that a new plant can sprout from

Cell Biology

Medium · 15×15 · 13 words
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Across

  1. 1. Organelle that stores a cell's genetic material
  2. 3. Type of cell division that produces two identical daughter cells
  3. 9. Network of protein fibers that gives a cell its shape and support
  4. 10. Movement of water through a membrane from an area of low to high concentration
  5. 11. Cell structure that packages and ships proteins to their destination
  6. 12. Complex cell type that contains a true nucleus
  7. 13. Type of cell division that produces reproductive cells with half the chromosomes

Down

  1. 2. Cell structure filled with enzymes that break down waste
  2. 4. Organelle known as the powerhouse that generates cellular energy
  3. 5. General term for any small specialized structure inside a cell
  4. 6. Cell structure that builds proteins
  5. 7. Ability of an organism to keep its internal conditions stable
  6. 8. Large molecule built by ribosomes that cells use for growth and repair

Cell Biology

Easy · 15×15 · 16 words
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Across

  1. 2. Tiny building block that makes up all living things
  2. 4. Living thing whose cells lack a rigid outer wall
  3. 6. Body part, like the heart or stomach, made of tissues
  4. 8. Small structure inside a cell that does a specific job
  5. 11. Jelly-like substance filling the inside of a cell
  6. 13. Control center of a cell that holds its DNA
  7. 15. Tiny single-celled organism found almost everywhere on Earth
  8. 16. Thin outer layer that holds a cell together and controls what enters

Down

  1. 1. Living thing whose cells contain chloroplasts
  2. 3. Cell part that produces energy for the cell to use
  3. 5. Rigid outer layer found in plant cells but not animal cells
  4. 7. Molecule inside cells that carries genetic instructions
  5. 9. Tool scientists use to see very small things like cells
  6. 10. Cell part that stores water, food, or waste
  7. 12. Group of similar cells working together
  8. 14. Describes anything made of cells that grows and reproduces

Photosynthesis

Medium · 15×15 · 14 words
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Across

  1. 2. Colored substance in leaves that absorbs sunlight
  2. 3. Waxy leaf coating that helps prevent water loss
  3. 5. Byproduct gas released when water molecules split
  4. 6. Simple sugar plants produce for energy
  5. 8. Outer protective layer of cells on a leaf
  6. 10. Tiny pores on leaves that exchange gases
  7. 11. Element found in the gas plants absorb from air
  8. 12. Molecule split apart during the light reactions

Down

  1. 1. Plant tissue that carries water upward from the roots
  2. 2. Plant tissue that carries sugar to other parts
  3. 3. Green pigment that captures light energy in leaves
  4. 4. Process that releases stored energy from sugar
  5. 7. Stored form of power found inside glucose
  6. 9. Main energy source that powers photosynthesis

Photosynthesis

Easy · 11×11 · 15 words
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Across

  1. 1. Mix of gases that surrounds every plant
  2. 5. Flat green part of a plant that catches sunlight
  3. 6. Dirt that holds nutrients for plant roots
  4. 8. Liquid that plant roots soak up from soil
  5. 10. Plant part that holds up the leaves and flowers
  6. 12. Tall plant with a thick wooden trunk
  7. 13. Common color of healthy plant leaves
  8. 14. What a plant makes using sunlight and water

Down

  1. 2. Underground plant part that takes in water
  2. 3. Colorful plant part that attracts bees
  3. 4. Living thing that makes its own food
  4. 7. Energy from the sun that plants need to grow
  5. 9. Power a plant gets from sunlight
  6. 10. Small part a new plant can grow from
  7. 11. Star that gives Earth light and heat

Biology

Easy · 7×7 · 8 words
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Across

  1. 3. Muscular organ that pumps blood through the body
  2. 5. Breathing organ situated within the rib cage
  3. 7. Molecule that carries genetic information
  4. 8. Green, flattened structure attached to a stem

Down

  1. 1. Tube forming part of the blood circulation system
  2. 2. Main upward stalk of a plant
  3. 4. Organism such as trees, shrubs, and herbs
  4. 6. Heredity unit transferred from a parent to offspring

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Biology Crossword FAQ

Is this Biology crossword puzzle free?

Yes. Every Biology crossword on this page is free. You can print it, download it as a PDF, or play it online without paying anything or creating an account.

Can I print the Biology crossword?

Yes. Click Print on any puzzle for a print-ready page with the grid, the clues, and a name and date line, or use Download to save it as a PDF, PNG, or JPEG for photocopying. The PDF download includes a filled answer key on the last page for grading.

Can students play these crosswords online?

Yes. Every puzzle has a Play online link that opens in the browser on any device. No app install and no signup is needed to play, which makes it easy to share with a class.

Can I make my own Biology crossword?

Yes. The free Grid Genius crossword maker builds a puzzle from your own words and clues, with a printable grid and answer key. The Grid Genius app can also generate a complete crossword from any topic you type.